Description

Treatment and prevention of infestations in dogs and cats: Nematodes caused by helminths of the Ancylostoma caninum, Toxocara canis, Toxascaris leonine, Trichuris vulpis, Uncinaria stenocephala species; Cestodoses caused by helminths of the species Dipylidium caninum, Taenia spp., Echinococcus multilocularis, Mesocestoides spp., Echinococcus granulosus, Multiceps multiceps. Composition: 1 tablet contains: Fenbendazole 500 mg; Praziquantel 50 mg. Excipients: sodium dodecyl sulfate; povidone K25; magnesium stearate sodium croscarmellose. Dosage form and packaging: Tablets for oral use, white, round, with a cruciform notch on one side. Packaged in 3 tablets in blisters, placed in a cardboard box. Pharmacological properties: Pharmacological group - anthelmintics. Veterinary ATC code: QP52AA51. Praziquantel (Praziquantel) - a compound of the group of pyrazinisoquinolines, active against cestodes, increases the permeability of helminth cell membranes for calcium ions, causes a generalized contraction of the muscles of the parasite, turning into permanent paralysis, which leads to the death of helminths. When administered orally, praziquantel is well absorbed in the intestine, reaching a maximum blood concentration in 1-4 hours, binds to plasma proteins (up to 80%), undergoes biotransformation in the liver with the formation of inactive mono- and polyhydroxylated metabolites. It is excreted from the body mainly with urine, and in small quantities - with feces. Fenbendazole (Fenbendazole) is a broad-spectrum anthelmintic agent, used in veterinary medicine and affects many intestinal parasites: lamblia, nematodes and cestodes, in particular tapeworms from the Taenia genus (but not effective against cucumber tapeworm) and some trematodes. Affects adults, as well as parasites in the larval stage and their eggs. The advantage lies in the absence of side effects or their minor manifestations. Indications for use: Treatment and prevention of infestations in dogs and cats: Nematodes caused by helminths of the Ancylostoma caninum, Toxocara canis, Toxascaris leonine, Trichuris vulpis, Uncinaria stenocephala species; Cestodoses caused by helminths of the species Dipylidium caninum, Taenia spp., Echinococcus multilocularis, Mesocestoides spp., Echinococcus granulosus, Multiceps multiceps. Dosage and method of administration: All animals in the family should undergo deworming at the same time. Weigh the animal before giving the medicine, the effectiveness of any drug depends on the accuracy of dosing. For pregnant and lactating bitches, the drug is used under the supervision of a veterinarian. A preliminary fasting diet and the use of laxatives before deworming are not required. Apply to dogs and cats once, individually in crushed form with food or injected forcibly on the root of the tongue in doses indicated in the table: 1 tablet per 10 kg of animal weight. Animal weight, kg Number of tablets Dogs to 10 1 10-20 2 20-30 3 Cats 4 0.5 8-12 1 Prophylaxis of animals is usually once a quarter (3 months) in the above doses, as well as 2 weeks before vaccination. In a family where there are small children who closely communicate with pets, it is advisable to deworm the animals once a month, for preventive purposes. Contraindications: Do not use in pregnant animals at the beginning of pregnancy; Do not use on sick and weakened animals; Do not administer to animals with impaired renal and liver function; Do not use in case of hypersensitivity to the drug. Side effects: In treated animals, due to deworming, sometimes vomiting or mild diarrhea is observed.